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What causes migraine headaches?

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In simple terms, migraines are thought to be caused by blood vessels in the brain that have become overexcited and have expanded. The chemical serotonin plays a role in this. When your serotonin levels are high, your blood vessels constrict (narrow). But when your serotonin is low, your blood vessels dilate (swell). This expansion or swelling leads to the throbbing or pulsating that causes migraine pain.

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